A Verdade sobre as Células Embrionárias
Dra. Alice Texeira Ferreira*
Eis a lista de mentiras que se divulgam sobre as células embrionárias:
1) A Igreja é obscurantista e impede o desenvolvimento da ciência:
A verdade é que querem acabar com a única instituição que defende o ser humano desde o inicio de sua vida que se dá na concepção até sua morte natural.Que o início da vida humana se dá quando o espermatozóide fecunda o óvulo já foi demonstrado em 1827 por Karl Ernst von Baer. Não é dogma da Igreja, pois somente com o acúmulo de evidencias sobre este FATO é que o Papa Pio IX em 1869 propôs que era dever da Igreja defender o embrião humano desde a concepção. Atualmente os embriologistas acrescentaram mais evidencias de que a fertilização é o inicio do inicio: Dra Magdalena Zernica-Goetz mostrou, em 2002, que a primeira divisão do zigoto não se dá por acaso, “ela já define o nosso destino”.
2) As células embrionárias humanas são pluripotentes e vão salvar vidas.
A verdade é que estas células não apresentam divisão assimétrica como as células-tronco. Elas são imortalizadas e são semelhantes às células cancerígenas; multiplicam-se rapidamente e quando se diferenciam logo morrem, não se renovando. Elas não se fixam nos nichos das células-tronco adultas presentes no organismo. Os corpos embrioides injetados são rejeitados imunologicamente e se injetados em animais imunossuprimidos geram câncer de caráter embrinário. Por isto não dispomos de exemplo de uma vida, mesmo de roedores, que tenha sido salva com estas células. Como diz a Dra. Lenise Garcia: “Que vidão terão estas células extraídas do embrião humano: viverão como câncer num camundongo.”
3) As células embrionárias podem transformar-se em todos os tecidos.
A verdade é que tal afirmação baseia-se no desenvolvimento embrionário, mas tal fato não foi demonstrado até hoje por problema metodológico: não existe uma tecnologia que permita distinguir todos os tipos de células do organismo humano. Eu trabalho com culturas de células há 20 anos e enfrento este problema corriqueiramente.
Neste artigo McGuckin demonstra também a pluripotência das células-tronco do sangue de cordão conseguindo observar a sua transformação em células nervosas. Fato também demonstrado por Prof. Dr. Paul Sanberg.PNAS, (2007), vol.104: 11869-11870.
4) As células embrionárias tem como fonte única o embrião que necessita ser estourado para se obter sua massa celular interna. A verdade é que existem outras fontes destas células: o líquido amniótico, as espermatogônias e oogônias que a PrimeCell consegue reverter para o estado embrionário e agora as iPCs( induced pluripotent cells, células pluripotentes por indução ) desenvolvidas por Dr. Yamanaka. Outra verdade é que este cientista, que eu conheço pessoalmente, diz que as informações necessárias para obter as iPCs foram obtidas de células embrionárias de CAMUNDONGO. Numa entrevista ele relatou que “numa clínica de reprodução assistida, ao observar num microscópio um embrião humano, tive mudada a minha carreira científica. Quando vi o embrião, de repente compreendi que havia muito pouca diferença entre ele e minhas filhas. Eu pensei, nós não podemos destruir embriões humanos em pesquisa. Tem de haver uma outra maneira de estudar as células embrionárias”.
5) Embriões humanos congelados por mais de 3 anos vão para o lixo pois não geram uma pessoa.
A verdade é que tem embrião humano congelado por até 13 anos que resultou numa criança saudável. São vários os exemplos que podem ser encontrados em http://www.youtube.com/watch?v=Pf9dI3UdWq0 Ao descongelar já é possível identificar se as células estão boas. Seestiverem vacuolizadas estão em processo de morte e não serve para nada pois não se obtém culturade células mortas.
6) Querem comparar o embrião na fase de blastocisto com o pacientedescerebrado do qual se colhe os órgão para transplante. A verdade é que o embrião contem o programa completo para gerar não só o cérebro como todos os demais órgãos, o que não ocorre com a morte cerebral que é irreversível.
7) As lesões de espinha dorsal só tem solução com transplante de células embrionárias humanas.
A verdade de acordo com Dr. DC Hess e CV Borlongan (Cell Proliferation, 2008, vol. 41(Suppl 1), 194-114) no artigo intitulado Stem Cells and neurological deseases, é que o cisto , a cavidade que se forma no local da lesão, é o grande obstáculo para a solução com transplante de células, seja células embrionárias seja células tronco adultas,. Mesmo se utilizadas as células expandidas sobre um arcabouço não se tem a formação das conecções entre as célula nervosas de maneira correta. O Dr. Carlos Alberto Moreira do Hospital Albert Einstein, apesar de ser favorável à pesquisa com células embrionárias (por outras razões, diga-se de passagem) e que estuda estas conecções (sinapses) concorda plenamente com este autores (Hess e Borlogan). Trata-se de uma hipótese muito remota de que as células embrionárias humanas servirão para terapia celular.
8) Finalmente, durante a conferência, que foi organizada pela Associação Nacional para a Defesa do Direito à Objeção de Consciência (ANDOC) na Academia de Medicina de Granada, a pesquisadora Natália López Moratalla, catedrática de Bioquímica da Universidade de Navarra, afirmou que hoje a pesquisa 'derivou decididamente para o emprego das células-tronco ‘adultas’, que são extraídas do próprio organismo e que já estão dando resultados na cura de doentes’. Segundo López Moratalla, «existem cerca de 600 protocolos que utilizam células-tronco adultas, e não se apresentou nenhum com células de origem embrionárias». As células adultas «possuem o mesmo potencial de crescimento e diferenciação das células-tronco embrionárias e substituem muito bem as possibilidades biotecnológicas sonhadas para aquelas».«As últimas descobertas sobre as possibilidades terapêuticas das células-tronco adultas, põem em suspeita abertamente as duas grandes ‘promessas’ propiciadas pela nova lei espanhola de biomedicina: o uso e criação de embriões para pesquisa e a chamada clonagem terapêutica. Aos graves problemas éticos já conhecidos (a destruição indiscriminada de milhares de embriões humanos), se unem evidências científicas que questionam cada vez sua utilidade terapêutica», afirmou a pesquisadora.«As células-tronco embrionárias fracassaram. Caiu, pelo peso de sua própria irracionalidade, o uso terapêutico de células provenientes de embriões gerados por fecundação, ou células humanas provenientes da transferência nuclear a óvulos (o que se conhece por clonagem terapêutica)», reiterou. Tendo em vista os esclarecimentos acima seria ético que se parasse com esse engodo que sugere que as células embrionárias humanas, obtidas com a morte de embriões humanos, vão fazer paralíticos andar, cego enxergar, etc.
*Dra. Alice Teixeira Ferreira, médica formada na Escola Paulista de Medicina em 1967, Doutorada
em Biologia Molecular em 1971, pos-doc na Research Division da Cleveland Clinic Foundation , EUA, Livre Docente da UNIFESP/EPM.
Fonte: http://blog.cancaonova.com/felipeaquino/2008/05/23/a-verdade-sobre-as-celulas-embrionarias/
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